Products are independently selected by our editors.
We may earn an affiliate commission from links.
I will be transparent, says the designer Azeeza Khan.
THE SUBSTANCEBoth celebrities and civilians are flocking to NAD+, hoping to stem the signs of aging. Photo: Ilan Rubin / trunkarchive.com.
The first time I heard about NAD+ was because Hailey Bieber was doing it.
(Her pal Kendall Jenner was partaking too.)
Khan insists she isnt one to crib longevity tips from famous 20-somethings, but her interest was piqued.
NAD+ is a common coenzyme that has become a target for algorithm-conscious wellness warriors and credentialed researchers alike.
We found that the production of NAD+ declines as we age, Imai says.
And it was safe, Tzoulis continues.
With no side effects.
He has since enrolled 400 patients in a more extensive follow-up trial, with results expected in June.
If it works, he adds, that will be big.
As Tzoulis cautions, though, dozens of promising interventions have failed in the past.
Neurological disorders, aging in generaltheyre thorny processes to disrupt.
These diseases are associated with aging, he says.
So people think, If NAD+ can help fight neurodegenerative disease, could I take it to prevent neurodegeneration?
With characteristic Norwegian bluntness, Tzoulis says scientists dont have an answer.
After that, hell investigate whether the general smoothie-imbibing population stands to benefit from supplementation.
Still, hes clear on his priorities.
He and his team did not get into the NAD+ game for the Goop crowd.
We were not looking at wellness.
We were not looking at wrinkles, he states.
Its too bad, per just about every doctor and researcher I speak to, that they dont work.
Tzoulis puts it in nonscientific terms: In very plain words, intramuscular and IV NAD+ intake is silly.
Still, there are several less-suspect delivery mechanisms.
Exercise can raise NAD+ levels.
Also promising, according to those marketing supplements, are inexpensive pills formulated with NAD+ precursors.
Those molecules are small enough to enter cells, where a series of chemical transformations turns them into NAD+.
(Guarentes Elysium offers two versions, and companies like Thorne and Renue sell their own products too.)
The Food and Drug Administration hasnt approved a single one, and the supplement marketplace remains unregulated.
It cheers him to think even further ahead.
He analogizes the decline in NAD+ over time to a basin filled with water that seems to be draining.
Is the problem that water isnt coming in, or is it that theres a leak?
Could that kind of discovery make septuagenarian runners reach personal bests?
Help DNA repair itself well into old age?
Make our hair glossier?
Is NAD+ better thanBotox?
Might I agree with influencers and celebrities about the virtues of asupplement?
The scientists are too sober to indulge me now.
But Im willing to wait.
