The first is of a fried egg being injected with a mysterious liquid.
Suddenly, the yolk splits into two and a second egg emerges from it.
This, in a nutshell, illustrates the medical procedure at the center of this mind-bending sci-fi thriller.

Photo: Mubi
Elisabeth is game: she places an order and receives a box with instructions.
After seven days, she must switch back for another week before the cycle continues.
Margaret Qualleys Sue looms over Demi Moores Elisabeth inThe Substance.

Margaret Qualley’s Sue looms over Demi Moore’s Elisabeth inThe Substance.
But when the time comes to return to her real body, a kind of depression descends.
When Elisabeth returns, she finds that shes beginning to age at a more rapid pace as a result.
In the end, she scrubs it all off her face in a rage.

Moore’s Elisabeth receiving The Substance.
It is, without doubt, the performance of her career.
Moores Elisabeth receiving The Substance.