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PDRN, or polydeoxyribonucleotide, is the active ingredient in salmon-sperm facials.

Sam Spence
Its a fragment of DNA, saysDr.
Eunice Park, dual-board-certified facial plastic and reconstructive surgeon and the founder ofAIREMin New York.
(Not outright sperm, as hype would lead you to believe.)

Vogues Favorite PDRN Skin-Care Products
The most common pro-grade treatment youll see is Rejuran Healing Essence.
Rather than injecting it, Park applies it to the skin aftermicroneedlingor lasering.
Its like a vitamin boost to the skin, she says.

These should all include a version of DNA fragments, says Fu.
However, the labels dont tell you where the DNA fragments would be sourced from.
How long does it take to see the results from PDRN?

Do topical PDRN products work as well as in-office treatments?
Deeper penetration of an active translates to more dramatic improvement in a faster amount of time.
However, the more affordable and convenient nature of at-home PDRN serums make them worthy of consideration.

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